EXAMINE THIS REPORT ON LSD CRYSTAL

From the LSD-certain crystal composition, the facet chain of the lid residue L209EL2 kinds intensive hydrophobic contacts with both LSD and bordering residues in TMs III, IV, and V (Determine 4C). Once the lid moved apart to show the binding pocket in simulation, various of such contacts broke. We Hence hypothesized that L209EL2 acts for a latch, l